Modulation of peripheral blood mononuclear cell activation status duringsalmonella-triggered reactive arthritis
نویسندگان
چکیده
منابع مشابه
Peripheral blood mononuclear cell activation induced by Leptospira interrogans glycolipoprotein.
Leptospira interrogans glycolipoprotein (GLP) has been implicated in pathological and functional derangement seen in leptospirosis. The goal of this study was to evaluate GLP's ability to induce cellular activation, as assessed by cytokine production and expression of surface activation markers. GLP extracted from either pathogenic L. interrogans serovar Copenhageni or nonpathogenic Leptospira ...
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Reactive arthritis (ReA) is an infection-induced systemic illness characterized by an aseptic inflammatory joint involvement and occurring in genetically predisposed patients with a bacterial infection localized in a distant organ or system. We evaluated the possible role of bacterial infection in the etiology of reactive arthritis by testing peripheral blood monocytes (PBMCs) for the presence ...
متن کاملtriggered reactive arthritis
Objectives-To report two patients who developed reactive arthritis in association with Staphylococcus aureus infection. Methods-A review of the case notes of two patients. Results-Two adult female patients have developed sterile arthritis in association with Staph aureus infection. The first patient has had two episodes of arthritis; the first followed olecranon bursitis, the second followed in...
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A ctivation-induced apoptosis is a critical mechanism by which the immune system maintains tolerance to self antigens by the clonal deletion of autoreactive T and B cells. The involvement of apoptosis in the mechanism of cell death induced by high doses of methotrexate (MTX) was first demonstrated in Chinese hamster ovary cells. Fas mediated apoptosis may have a critical role in the regression ...
متن کاملThe Elevated Secreted Immunoglobulin D Enhanced the Activation of Peripheral Blood Mononuclear Cells in Rheumatoid Arthritis
Immunoglobulin D (IgD) is a surface immunoglobulin that is expressed as either membrane IgD (mIgD) or secreted IgD (sIgD). Researchers have shown that sIgD is often elevated in patients with autoimmune diseases. The possible roles of sIgD on the function of peripheral blood mononuclear cells (PBMCs) in rheumatoid arthritis (RA) are still unclear. In this study, we compared the expression of sIg...
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ژورنال
عنوان ژورنال: Arthritis & Rheumatism
سال: 1999
ISSN: 0004-3591,1529-0131
DOI: 10.1002/1529-0131(199910)42:10<2045::aid-anr4>3.0.co;2-e